Key features and details
- Rabbit polyclonal to HELZ2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-HELZ2 antibody
DescriptionRabbit polyclonal to HELZ2
ab129781 detects endogenous levels of total HELZ2 protein.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human HELZ2 (internal sequence).
- Extracts from Jurkat cells
This product was previously labelled as PR285
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 49% PBS
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab129781 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Our Abpromise guarantee covers the use of ab129781 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 295 kDa.|
FunctionHelicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.
Tissue specificityExpressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta.
Sequence similaritiesBelongs to the DNA2/NAM7 helicase family.
Contains 1 C2H2-type zinc finger.
DomainContains 5 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. These motifs are not required for interaction with PPARG.
- Information by UniProt
- ATP-dependent helicase PRIC285 antibody
- KIAA1769 antibody
- PDIP1 antibody
ab129781 has been referenced in 1 publication.
- Fusco DN et al. HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus. Front Microbiol 8:240 (2017). PubMed: 28265266