Key features and details
- Mouse monoclonal [16B12] to Hemagglutinin (DyLight® 488)
- Suitable for: ICC/IF, Flow Cyt
- Conjugation: DyLight® 488. Ex: 493nm, Em: 518nm
- Isotype: IgG1
Product nameAnti-Hemagglutinin antibody [16B12] (DyLight® 488)
See all Hemagglutinin primary antibodies
DescriptionMouse monoclonal [16B12] to Hemagglutinin (DyLight® 488)
ConjugationDyLight® 488. Ex: 493nm, Em: 518nm
Tested applicationsSuitable for: ICC/IF, Flow Cytmore details
The influenza hemagglutinin epitope (YPYDVPDYA).
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 1.6% Sodium phosphate, 0.88% Sodium chloride, 1% BSA
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab117488 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||1/500 - 1/5000.|
|Flow Cyt||Use at an assay dependent concentration.|
RelevanceHemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
Cellular localizationCell membrane; apical cell membrane; single-pass type I membrane protein.
- HA antibody
- HA1 antibody
- HA2 antibody
- Hemagglutinin antibody
ab117488 staining Hemagglutinin in Monkey cos7 cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde. Samples were incubated with primary antibody (1/100) for 1 hour at 22°C.
ab117488 has not yet been referenced specifically in any publications.