Key features and details
- Chicken polyclonal to Hemagglutinin (HRP)
- Suitable for: WB, ELISA
- Reacts with: Influenza A
- Conjugation: HRP
- Isotype: IgY
Product nameAnti-Hemagglutinin antibody (HRP)
See all Hemagglutinin primary antibodies
DescriptionChicken polyclonal to Hemagglutinin (HRP)
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Influenza A
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
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Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.00
Preservative: 0.005% Thimerosal (merthiolate)
Constituents: 0.6% HEPES, 0.29% Sodium chloride, 0.1% BSA, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAfter multiple immunizations in Freunds adjuvant, eggs were collected and the immunoglobulin fraction prepared. Antibodies were immunoaffinity purified using the peptide immobilized on a solid support and the antibodies were conjugated to horseradish peroxidase (HRP).
Our Abpromise guarantee covers the use of ab190060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The anti HA diluted 1:5,000 gives an O.D.= 1.0 in a 15 minute reaction against peptide conjugated to a different carrier than used for anti peptide purification
RelevanceHemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
Cellular localizationCell membrane; apical cell membrane; single-pass type I membrane protein.
- HA antibody
- HA1 antibody
- HA2 antibody
- Hemagglutinin antibody
ab190060 has not yet been referenced specifically in any publications.