Anti-Heme Oxygenase 1 antibody (ab82585)
Key features and details
- Rabbit polyclonal to Heme Oxygenase 1
- Suitable for: WB
- Reacts with: Mouse, Rat, Dog, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
-
Product name
Anti-Heme Oxygenase 1 antibody
See all Heme Oxygenase 1 primary antibodies -
Description
Rabbit polyclonal to Heme Oxygenase 1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Dog, Human -
Immunogen
Synthetic peptide from the N terminal of Human Heme Oxygenase 1
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab82585 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
|
Notes |
---|
WB
1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa). |
Target
-
Function
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. -
Sequence similarities
Belongs to the heme oxygenase family. -
Cellular localization
Microsome. Endoplasmic reticulum. - Information by UniProt
-
Database links
- Entrez Gene: 442987 Dog
- Entrez Gene: 3162 Human
- Entrez Gene: 15368 Mouse
- Entrez Gene: 24451 Rat
- Omim: 141250 Human
- SwissProt: P09601 Human
- SwissProt: P14901 Mouse
- SwissProt: P06762 Rat
see all -
Alternative names
- 32 kD antibody
- bK286B10 antibody
- D8Wsu38e antibody
see all
Images
-
All lanes : Anti-Heme Oxygenase 1 antibody (ab82585) at 1/1000 dilution
Lane 1 : Heme Oxygenase 1 Recombinant Rat Protein
Lane 2 : Heme Oxygenase 1 Recombinant Human Protein
Lane 3 : Heme Oxygenase 2 Recombinant Human Protein
Lane 4 : Dog Liver Microsome Extract
Lane 5 : Mouse Liver Microsome Extract
Lane 6 : Rat Liver Microsome Extract
Lane 7 : Human Liver Microsome Extract
Developed using the ECL technique.
Predicted band size: 33 kDa
Observed band size: 33 kDa
Datasheets and documents
-
SDS download
-
Datasheet download
References (4)
ab82585 has been referenced in 4 publications.
- Uto K et al. Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation. BMC Gastroenterol 19:25 (2019). PubMed: 30736744
- Barta T et al. Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies. Naunyn Schmiedebergs Arch Pharmacol 391:371-383 (2018). WB ; Rat . PubMed: 29354880
- Liu X et al. Effects of ginsenoside Rb1 on oxidative stress injury in rat spinal cords by regulating the eNOS/Nrf2/HO-1 signaling pathway. Exp Ther Med 16:1079-1086 (2018). PubMed: 30116359
- Wang Y et al. Retinoprotective Effects of Bilberry Anthocyanins via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Mechanisms in a Visible Light-Induced Retinal Degeneration Model in Pigmented Rabbits. Molecules 20:22395-410 (2015). PubMed: 26694327