Product nameAnti-Hemoglobin A1c antibody
See all Hemoglobin A1c primary antibodies
DescriptionDuck polyclonal to Hemoglobin A1c
SpecificityThis antibody is specific to Hemoglobin A1c.
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Human
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.0268% PBS, 0.812% Sodium chloride
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurity was determined by SDS PAGE (blue stain), showing that the IgY(delta Fc) constitute was 90% of total protein, and the IgY and IgY (delta Fc) constitute was 95% of total protein.
Our Abpromise guarantee covers the use of ab31151 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Immunochromatography: Use at an assay dependent dilution.
Immunoturbidimetry: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionInvolved in oxygen transport from the lung to the various peripheral tissues.
LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure.
Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
Tissue specificityRed blood cells.
Involvement in diseaseHeinz body anemias
Sickle cell anemia
Beta-thalassemia, dominant, inclusion body type
Sequence similaritiesBelongs to the globin family.
modificationsGlucose reacts non-enzymatically with the N-terminus of the beta chain to form a stable ketoamine linkage. This takes place slowly and continuously throughout the 120-day life span of the red blood cell. The rate of glycation is increased in patients with diabetes mellitus.
S-nitrosylated; a nitric oxide group is first bound to Fe(2+) and then transferred to Cys-94 to allow capture of O(2).
Acetylated on Lys-60, Lys-83 and Lys-145 upon aspirin exposure. PubMed:16916647 reports the identification of HBB acetylated on Lys-145 in the cytosolic fraction of HeLa cells. This may have resulted from contamination of the sample.
- Information by UniProt
- Beta-globin antibody
- HBB antibody
- HBB_HUMAN antibody
ab31151 has not yet been referenced specifically in any publications.