Key features and details
- Sheep polyclonal to Hemoglobin A1c
- Suitable for: ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Hemoglobin A1c antibody
DescriptionSheep polyclonal to Hemoglobin A1c
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Human
Hemoglobin A1C (human)
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
(before addition of glycerol)Constituents: 40% Glycerol, PBS, pH 7.4
Concentration information loading...
Our Abpromise guarantee covers the use of ab33615 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
FunctionInvolved in oxygen transport from the lung to the various peripheral tissues.
LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure.
Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
Tissue specificityRed blood cells.
Involvement in diseaseHeinz body anemias
Sickle cell anemia
Beta-thalassemia, dominant, inclusion body type
Sequence similaritiesBelongs to the globin family.
modificationsGlucose reacts non-enzymatically with the N-terminus of the beta chain to form a stable ketoamine linkage. This takes place slowly and continuously throughout the 120-day life span of the red blood cell. The rate of glycation is increased in patients with diabetes mellitus.
S-nitrosylated; a nitric oxide group is first bound to Fe(2+) and then transferred to Cys-94 to allow capture of O(2).
Acetylated on Lys-60, Lys-83 and Lys-145 upon aspirin exposure. PubMed:16916647 reports the identification of HBB acetylated on Lys-145 in the cytosolic fraction of HeLa cells. This may have resulted from contamination of the sample.
- Information by UniProt
- Beta-globin antibody
- HBB antibody
- HBB_HUMAN antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab33615 has not yet been referenced specifically in any publications.