Key features and details
- Rabbit polyclonal to Hemoglobin subunit gamma 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Hemoglobin subunit gamma 2 antibody
DescriptionRabbit polyclonal to Hemoglobin subunit gamma 2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to a region within amino acids 1-97 of Human Hemoglobin subunit gamma 2 (Uniprot ID: P69892).
- U87-MG whole cell lysate
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab153898 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 16 kDa.|
FunctionGamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Tissue specificityRed blood cells.
Involvement in diseaseDefects in HBG2 are the cause of cyanosis transient neonatal (TNCY) [MIM:613977]. TNCY is a disorder characterized by cyanosis in the fetus and neonate, due to a defect in the fetal hemoglobin chain which has reduced affinity for oxygen. Some patients develop anemia resulting from increased destruction of red cells containing abnormal or unstable hemoglobin. The cyanosis resolves spontaneously by 5 to 6 months of age or earlier, as the adult beta-globin chain is produced and replaces the fetal gamma-globin chain.
Sequence similaritiesBelongs to the globin family.
Developmental stageExpressed until four or five weeks after birth.
modificationsAcetylation of Gly-2 converts Hb F to the minor Hb F1.
- Information by UniProt
- Abnormal hemoglobin antibody
- FLJ76540 antibody
- G gamma globin antibody
ab153898 has not yet been referenced specifically in any publications.