Key features and details
- Selective A2A receptor agonist
- CAS Number: 141018-30-6
- Soluble in DMSO to 100 mM and in ethanol to 50 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Product nameHENECA, A2A receptor agonist
DescriptionSelective A2A receptor agonist
Selective A2A receptor agonist (Ki = 2.2 nM). Shows good selectivity for A2A over A1 receptors. Displays antiaggregatory activity. Increases cAMP accumulation (EC50 = 43 nM) and inhibits superoxide anion production (EC50 = 3.63 nM) in neutrophils.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 50 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120458 has been referenced in 1 publication.
- Nagpure BV & Bian JS Hydrogen sulfide inhibits A2A adenosine receptor agonist induced ß-amyloid production in SH-SY5Y neuroblastoma cells via a cAMP dependent pathway. PLoS One 9:e88508 (2014). PubMed: 24523906