Overview

  • Product name

    HENECA, A2A receptor agonist
  • Description

    Selective A2A receptor agonist
  • Biological description

    Selective A2A receptor agonist (Ki = 2.2 nM). Shows good selectivity for A2A over A1 receptors. Displays antiaggregatory activity. Increases cAMP accumulation (EC50 = 43 nM) and inhibits superoxide anion production (EC50 = 3.63 nM) in neutrophils.
  • Purity

    > 99%
  • CAS Number

    141018-30-6
  • Chemical structure

    Chemical Structure

Properties

Images

  • Concentration-dependent effect of HENECA (10-200 nM, 24 hours) on Aβ42 production.

References

This product has been referenced in:

  • Varani K  et al. Effect of low frequency electromagnetic fields on A2A adenosine receptors in human neutrophils. Br J Pharmacol 136:57-66 (2002). Read more (PubMed: 11976268) »
  • Varani K  et al. Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects. Circulation 102:285-9 (2000). Read more (PubMed: 10899090) »
  • Monopoli A  et al. Pharmacology of the new selective A2a adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine. Arzneimittelforschung 44:1296-304 (1994). Read more (PubMed: 7848347) »
See 1 Publication for this product

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