Anti-Hepatitis B Virus Core Antigen antibody (ab115992)
- Datasheet
- References (4)
- Protocols
Overview
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Product name
Anti-Hepatitis B Virus Core Antigen antibody
See all Hepatitis B Virus Core Antigen primary antibodies -
Description
Rabbit polyclonal to Hepatitis B Virus Core Antigen -
Host species
Rabbit -
Specificity
Serotype specificity information is not available for this antibody
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Tested applications
Suitable for: IHC-P, IHC-Frmore details -
Species reactivity
Reacts with: Hepatitis B virus -
Immunogen
Full length native protein (purified) corresponding to Hepatitis B Virus Core Antigen.
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Positive control
- Human liver tissue infected with Hepatitis B virus.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1.17% Sodium chloride, 0.16% Sodium phosphate -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab115992 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | 1/200 - 1/400. | |
IHC-Fr | 1/200 - 1/400. |
Target
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Relevance
Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection. -
Cellular localization
Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus. -
Database links
- Entrez Gene: 2828293 Hepatitis B virus
- Entrez Gene: 944568 Hepatitis B virus
- SwissProt: P03146 Hepatitis B virus
- SwissProt: P03147 Hepatitis B virus
- SwissProt: P03148 Hepatitis B virus
- SwissProt: P0C573 Hepatitis B virus
- SwissProt: P69706 Hepatitis B virus
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Alternative names
- C antibody
- Capsid protein antibody
- Core and e antigen antibody
see all
Protocols
Datasheets and documents
References
This product has been referenced in:
- Liu J et al. Pathological Pattern of Intrahepatic HBV in HCC is Phenocopied by PDX-Derived Mice: a Novel Model for Antiviral Treatment. Transl Oncol 12:1138-1146 (2019). Read more (PubMed: 31202090) »
- Corcuera A et al. Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro. Antiviral Res 158:135-142 (2018). Read more (PubMed: 30031759) »