Overview

  • Product name

    Anti-Hepatitis B Virus Core Antigen antibody
    See all Hepatitis B Virus Core Antigen primary antibodies
  • Description

    Rabbit polyclonal to Hepatitis B Virus Core Antigen
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Hepatitis B virus
  • Immunogen

    HBcAg purified from the lysates of E.coli infected with the viral core DNA.

  • Positive control

    • Liver infected with the Hepatitis type B virus.
  • General notes


    This antibody detectes the antigen in the nuclei of the liver cells of the Hepatitis type B virus infected patients. However, occasional staining may also be seen in the perinuclear cytoplasm of the infected cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: 1% BSA
  • Concentration information loading...
  • Purity

    Proprietary Purification
  • Primary antibody notes

    This antibody detectes the antigen in the nuclei of the liver cells of the Hepatitis type B virus infected patients. However, occasional staining may also be seen in the perinuclear cytoplasm of the infected cells.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/150.

 An incubation period of 30 minutes at room temperature is recommended.

Target

  • Relevance

    Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
  • Cellular localization

    Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
  • Database links

    • Alternative names

      • C antibody
      • Capsid protein antibody
      • Core and e antigen antibody
      • core antibody
      • Core antigen antibody
      • Core protein antibody
      • HBc antibody
      • HBcAg antibody
      • HBVgp4 antibody
      • Hepatitis B core antigen antibody
      • Hepatitis B Virus core antigen antibody
      • p21.5 antibody
      • precore/core protein antibody
      see all

    References

    ab17228 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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