Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted (ab859)


  • Product name

    Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted
    See all Hepatitis B Virus Surface Antigen primary antibodies
  • Description

    Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
  • Host species

  • Specificity

    This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
  • Tested applications

    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity

    Reacts with: Hepatitis B virus
  • Immunogen

    BALB/c mice were immunized with purified HBsAG subtype AYW3.



Our Abpromise guarantee covers the use of ab859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
    No further titration is required.
    We suggest an incubation period of 60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
  • Target

    • Relevance

      Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
    • Cellular localization

      Virion membrane
    • Database links

      • Alternative names

        • Large envelope protein antibody
        • Large surface protein antibody
        • LHB antibody
        • Major surface antigen antibody


      ab859 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      1-3 of 3 Abreviews or Q&A


      Thank you for your email.
      We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
      If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet in the "specificity" section.
      Here is a non- exhaustive list of antibodies that bind all four major serotypes. They have even been characterized further and the datasheet will tell you the serotype subtypes (e.g. ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-)also.
      For example:
      ab2039 (or use the following:
      ab8333 (or use the following:
      ab859 (or use the following:
      ab20724 (or use the following:
      Which antibody is the most suitable for experiments depends on your samples and the planned application.
      We encourage customers to consult the latest literature available through PubMed and other resources in order to find the most up-to-date information about this specific research topic.
      I hope this information is helpful. Please do not hesiate to contact me again with anyfurther questions.

      Read More


      Regarding ab859 (Hepatitis B Virus Surface Antigen antibody [3E7], prediluted), the concentration of the present lot is 2 ug/ml. Please don't hesitate to contact us again if you have further questions.

      Read More


      The final concentration of this prediluted antibody is 20ug/ml.

      Read More

      For licensing inquiries, please contact

      Sign up