Key features and details
- Rabbit polyclonal to Hepatitis B Virus Surface Antigen
- Suitable for: ELISA
- Reacts with: Hepatitis B virus
- Isotype: IgG
Product nameAnti-Hepatitis B Virus Surface Antigen antibody
See all Hepatitis B Virus Surface Antigen primary antibodies
DescriptionRabbit polyclonal to Hepatitis B Virus Surface Antigen
SpecificityAb19979 reacts only with Hepatitis B surface antigen. Non-reactive with normal human serum.
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Hepatitis B virus
Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 0.0268% PBS
Concentration information loading...
PurityProtein A purified
Purification notes>95% pure.
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab19979 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
May be used in place of whole antiserum in almost any appropriate antibody based technique. Also suitable for conjugation purposes.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Cellular localizationVirion membrane
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab19979 has been referenced in 1 publication.
- Schliehe C et al. Stable antigen is most effective for eliciting CD8+ T-cell responses after DNA vaccination and infection with recombinant vaccinia virus in vivo. J Virol 86:9782-93 (2012). PubMed: 22761378