Anti-Hepatitis B Virus Surface Antigen antibody [B1929M] (ab252714)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Hepatitis B Virus Surface Antigen antibody [B1929M]
See all Hepatitis B Virus Surface Antigen primary antibodies -
Description
Mouse monoclonal [B1929M] to Hepatitis B Virus Surface Antigen -
Host species
Mouse -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Predicted to work with: Hepatitis B virus
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Immunogen
Recombinant full length protein corresponding to Hepatitis B virus Hepatitis B Virus Surface Antigen. Recombinant HBsAg of adr subtype.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: 1.64% Sodium phosphate, 0.87% Sodium chloride -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
Purified from tissue culture supernatant. = 98% pure (SDS-PAGE). -
Clonality
Monoclonal -
Clone number
B1929M -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab252714 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | Use at an assay dependent concentration. |
Target
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Relevance
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. -
Cellular localization
Virion membrane -
Database links
- Entrez Gene: 2703546 Hepatitis B virus
- SwissProt: P03142 Hepatitis B virus
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Alternative names
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
Datasheets and documents
References
ab252714 has not yet been referenced specifically in any publications.
