Key features and details
- Rabbit polyclonal to Hepatitis B Virus Surface Antigen (FITC)
- Suitable for: ICC/IF
- Reacts with: Hepatitis B virus
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameAnti-Hepatitis B Virus Surface Antigen antibody (FITC)
See all Hepatitis B Virus Surface Antigen primary antibodies
DescriptionRabbit polyclonal to Hepatitis B Virus Surface Antigen (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
SpecificityMonospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. This product is non-reactive with normal human serum.
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Hepatitis B virus
Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.
Covalently coupled with high purity Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.0268% PBS, 1% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab21021 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Cellular localizationVirion membrane
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab21021 has been referenced in 1 publication.
- Li G et al. Recombinant covalently closed circular DNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model. Hepatology 67:56-70 (2018). PubMed: 28749559