Anti-Hepatitis B Virus Surface Antigen antibody [HB5] (ab8333)

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Overview

  • Product name
    Anti-Hepatitis B Virus Surface Antigen antibody [HB5]
    See all Hepatitis B Virus Surface Antigen primary antibodies
  • Description
    Mouse monoclonal [HB5] to Hepatitis B Virus Surface Antigen
  • Host species
    Mouse
  • Specificity
    Recognizes following Hepatitis B virus subtypes:ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq- Specificity of MAb HB5 was verified by ELISA on panel of International Workshop on HBsAg Subtypes (Paris, April 1975). This antibody does not cross-block with ab8256 and is therefore suitable for use with ab8256 as a matched pair.
  • Tested applications
    Suitable for: ICC, ELISAmore details
  • Species reactivity
    Reacts with: Hepatitis B virus
  • Immunogen

    purified HbsAg from human plasma

Properties

Applications

Our Abpromise guarantee covers the use of ab8333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

Target

  • Relevance
    Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
  • Cellular localization
    Virion membrane
  • Database links
    • Alternative names
      • Large envelope protein antibody
      • Large surface protein antibody
      • LHB antibody
      • Major surface antigen antibody

    References

    ab8333 has not yet been referenced specifically in any publications.

    Publishing research using ab8333? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    2 reviews or Q&A

    10
    Votes: Highest First

    Hi Abcam Tech Support Team,

    May I know which Human HBsAg Monoclonal antibody (i.e. ab110600, ab54247 and ab20724) binds to all four serotypes of Hepatitis B virus?

    I look forward to receiving your reply soon. Many thanks in advanc...

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    Thank you for your email.
    We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
    If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet ...

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    I am interested in developing an Elisa to quantify mouse antibody titres against HBs virus and I am looking for a source of antibody to use as a positive control, I would be interested if you could tell me more information about the mouse monoclonal an...

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    All the information that we have is available on the datasheets, this includes the price in euros. You can order directly through the Abcam website or if you would prefer you can order from a distributor. There is an ordering section on the Abcam websi...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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