Product nameAnti-Hepatitis C Virus NS5a antibody [H26]
DescriptionMouse monoclonal [H26] to Hepatitis C Virus NS5a
SpecificityHepatitis C Virus antigen NS5a. This antibody works with the HCV genotypes 1a, 1b, 3 and 4, but not with genotype 2a.
Tested applicationsSuitable for: ELISA, WB, ICC/IFmore details
Recombinant full length protein (E. coli).
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab13833 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
RelevanceHCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008).
- HCV antibody
- HCV Non-structural protein 5A antibody
- Non-structural protein 5A antibody
This product has been referenced in:
- Kuwashiro T et al. Regulation of interferon signaling and HCV-RNA replication by extracellular matrix. Int J Mol Med 42:957-965 (2018). Read more (PubMed: 29786754) »
- Madhvi A et al. A screen for novel hepatitis C virus RdRp inhibitor identifies a broad-spectrum antiviral compound. Sci Rep 7:5816 (2017). Read more (PubMed: 28725041) »