Overview

  • Product name

    Anti-HePTP / PTPN7 antibody
  • Description

    Rabbit polyclonal to HePTP / PTPN7
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human HePTP/ PTPN7 aa 1-190.
    Database link: P35236

  • Positive control

    • IHC-P: Human liver cancer and tonsil tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab230004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • Tissue specificity

    Expressed exclusively in thymus and spleen.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications

    Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BPTP 4 antibody
    • BPTP4 antibody
    • Dual specificity phosphatase 1 antibody
    • Hematopoietic protein tyrosine phosphatase antibody
    • Hematopoietic protein-tyrosine phosphatase antibody
    • HEPTP antibody
    • LC PTP antibody
    • LCPTP antibody
    • LPTP antibody
    • Protein tyrosine phoshatase non receptor type stress induced antibody
    • Protein tyrosine phoshatase nonreceptor type stress induced antibody
    • Protein tyrosine phosphatase LC PTP antibody
    • Protein tyrosine phosphatase non receptor type 7 antibody
    • Protein-tyrosine phosphatase LC-PTP antibody
    • PTN7_HUMAN antibody
    • PTPN 7 antibody
    • Ptpn7 antibody
    • PTPNI antibody
    • Tyrosine protein phosphatase non receptor type 7 antibody
    • Tyrosine-protein phosphatase non-receptor type 7 antibody
    see all

Images

  • Paraffin-embedded human tonsil tissue stained for HePTP / PTPN7 using ab230004 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human liver cancer tissue stained for HePTP / PTPN7 using ab230004 at 1/100 dilution in immunohistochemical analysis.

References

ab230004 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230004.
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