Anti-HERC6 antibody (ab99949)
Key features and details
- Rabbit polyclonal to HERC6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-HERC6 antibody -
Description
Rabbit polyclonal to HERC6 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment, corresponding to amino acids 123 - 393 of Human HERC6 (BC035775).
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Positive control
- WB: HeLa cell lysate. IHC-P: fetal testis tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab99949 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Detects a band of approximately 115 kDa (predicted molecular weight: 115 kDa).
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IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/1000 - 1/2000. Detects a band of approximately 115 kDa (predicted molecular weight: 115 kDa). |
IHC-P
1/100 - 1/500. |
Target
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Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. -
Tissue specificity
Detected in brain, heart, placenta and testis. -
Pathway
Protein modification; protein ubiquitination. -
Sequence similarities
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 5 RCC1 repeats. -
Developmental stage
Expressed in fetal brain. -
Cellular localization
Cytoplasm > cytosol. - Information by UniProt
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Database links
- Entrez Gene: 55008 Human
- Entrez Gene: 67138 Mouse
- Entrez Gene: 362376 Rat
- Omim: 609249 Human
- SwissProt: Q8IVU3 Human
- SwissProt: F2Z461 Mouse
- Unigene: 529317 Human
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Alternative names
- EC 6.3.2. antibody
- FLJ20637 antibody
- HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 antibody
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Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab99949 has not yet been referenced specifically in any publications.