Anti-HES6 antibody (ab172800)
- Datasheet
- References
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Overview
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Product nameAnti-HES6 antibody
See all HES6 primary antibodies -
DescriptionMouse polyclonal to HES6
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse
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Immunogen
Full length protein corresponding to Human HES6 aa 1-224.
Sequence:MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRL LLAGAEVQAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGY IQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQDLLGDALA GPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEG PDLVPAALGSLTTAQIARSVWRPW
Database link: NP_061115.2 -
Positive control
- HES6 transfected 293T cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.2
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab172800 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. |
Target
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RelevanceHES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.
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Cellular localizationNuclear
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Database links
- Entrez Gene: 55502 Human
- Entrez Gene: 55927 Mouse
- Omim: 610331 Human
- SwissProt: Q96HZ4 Human
- SwissProt: Q9JHE6 Mouse
- Unigene: 42949 Human
- Unigene: 280029 Mouse
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Alternative names
- bHLHb41 antibody
- bHLHc23 antibody
- C HAIRY1 antibody
see all
Images
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Western blot - Anti-HES6 antibody (ab172800)All lanes : Anti-HES6 antibody (ab172800) at 1 µg/ml
Lane 1 : HES6 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 24 kDa
Protocols
Datasheets and documents
References
ab172800 has not yet been referenced specifically in any publications.
