Overview

  • Product name

  • Description

    Rabbit polyclonal to HES6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human HES6 (internal sequence). The exact sequence is proprietary.
    Database link: Q96HZ4

  • Positive control

    • WB: A549 whole cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab229776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 24 kDa.

Target

  • Relevance

    HES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • bHLHb41 antibody
    • bHLHc23 antibody
    • C HAIRY1 antibody
    • Class B basic helix-loop-helix protein 41 antibody
    • Hairy and enhancer of split 6 antibody
    • Hairy/enhancer of split 6, Drosophila, homolog of, 6 antibody
    • HES 6 antibody
    • hes family bHLH transcription factor 6 antibody
    • Transcription cofactor HES6 antibody
    see all

Images

  • Anti-HES6 antibody (ab229776) at 1/500 dilution + A549 (Human lung carcinoma cell line) whole cell extracts at 30 µg

    Developed using the ECL technique.

    Predicted band size: 24 kDa



    15% SDS-PAGE

References

ab229776 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229776.
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