Key features and details
- Potent, selective 20-HETE synthase inhibitor
- CAS Number: 339068-25-6
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameHET-0016, 20-HETE synthase inhibitor
DescriptionPotent, selective 20-HETE synthase inhibitor
Biological descriptionInhibits 20-HETE production (IC50 values are 18, 12 and 21 nM for CPY4A1, 4A2 and 4A3 respectively). Increases renal blood flow and inhibits cerebral ischemic damage in vivo. Crosses the blood-brain barrier.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141587 has not yet been referenced specifically in any publications.