Overview

  • Product name
    Anti-Hex antibody [HHE5I261]
    See all Hex primary antibodies
  • Description
    Mouse monoclonal [HHE5I261] to Hex
  • Host species
    Mouse
  • Specificity
    This antibody reacts with Hex.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Hex recombinant fragment (Human), containing 50-200 AAs from near the N-terminal.

Properties

Applications

Our Abpromise guarantee covers the use of ab50836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 43 kDa.
ELISA Use at an assay dependent dilution.

Target

  • Function
    Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
  • Tissue specificity
    Liver and promyelocytic leukemia cell line HL60.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
  • Developmental stage
    Expressed during hematopoiesis.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • Hematopoietically expressed homeobox antibody
      • Hematopoietically-expressed homeobox protein HHEX antibody
      • HEX antibody
      • HHEX antibody
      • HHEX_HUMAN antibody
      • HMPH antibody
      • Homeobox hematopoietically expressed antibody
      • Homeobox protein HEX antibody
      • Homeobox protein PRH antibody
      • HOX11L PEN antibody
      • PRH antibody
      • PRHX antibody
      • Proline rich homeodomain containing transcription factor antibody
      see all

    Images

    • Western blot - Anti-Hex antibody [HHE5I261] (ab50836)
      Western blot - Anti-Hex antibody [HHE5I261] (ab50836)
      Anti-Hex antibody [HHE5I261] (ab50836)
      Observed band size: 43 kDa (why is the actual band size different from the predicted?)



      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References

    ab50836 has not yet been referenced specifically in any publications.

    Publishing research using ab50836? Please let us know so that we can cite the reference in this datasheet.

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