Hexanoyl glycine, Acyl amino acid derivative (ab144992)

Overview

  • Product name

    Hexanoyl glycine, Acyl amino acid derivative
  • Description

    Acyl amino acid derivative.
  • Alternative names

    • Caproylglycine
    • N-(1-Oxohexyl)glycine
    • N-Caproylglycine
    • n-Hexanoylglycine
    • NSC 224460
    see all
  • Biological description

    Acyl amino acid derivative used as a urinary biomarker for several indications. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation.

  • CAS Number

    24003-67-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-(1-Oxohexyl)glycine
  • Molecular weight

    173.21
  • Molecular formula

    C8H15NO3
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Tyburski JB  et al. Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice. Radiat Res 170:1-14 (2008). Read more (PubMed: 18582157) »
  • Tserng KY  et al. Abnormal urinary excretion of unsaturated dicarboxylic acids in patients with medium-chain acyl-CoA dehydrogenase deficiency. J Lipid Res 31:763-71 (1990). Read more (PubMed: 2380628) »
  • Rinaldo P  et al. Medium-chain acyl-CoA dehydrogenase deficiency. Diagnosis by stable-isotope dilution measurement of urinary n-hexanoylglycine and 3-phenylpropionylglycine. N Engl J Med 319:1308-13 (1988). Read more (PubMed: 3054550) »

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