Overview

  • Product name

    Anti-HEXIM1 antibody [2416C2a]
    See all HEXIM1 primary antibodies
  • Description

    Mouse monoclonal [2416C2a] to HEXIM1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Dot blotmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment of human HEXIM1

Properties

Applications

Our Abpromise guarantee covers the use of ab58624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 41 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Function

    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
  • Tissue specificity

    Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
  • Sequence similarities

    Belongs to the HEXIM family.
  • Domain

    The coiled-coil domain mediates oligomerization.
  • Cellular localization

    Nucleus. Cytoplasm. Binds alpha-importin and is mostly nuclear.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cardiac lineage protein 1 antibody
    • CLP 1 antibody
    • CLP1 antibody
    • EDG 1 antibody
    • EDG1 antibody
    • Estrogen down-regulated gene 1 protein antibody
    • FLJ13562 antibody
    • Hexamethylene bis acetamide inducible 1 antibody
    • Hexamethylene bis acetamide inducible protein antibody
    • Hexamethylene bis acetamide inducible transcript 1 antibody
    • Hexamethylene bis-acetamide-inducible protein 1 antibody
    • HEXI1_HUMAN antibody
    • HEXIM 1 antibody
    • Hexim1 antibody
    • HEXIM1 protein antibody
    • HIS 1 antibody
    • HIS1 antibody
    • HMBA inducible antibody
    • MAQ 1 antibody
    • MAQ1 antibody
    • Menage a quatre 1 antibody
    • Menage a quatre protein 1 antibody
    • Protein HEXIM1 antibody
    see all

Images

  • Anti-HEXIM1 antibody [2416C2a] (ab58624) + immunogen (recombinant pfragment)

    Predicted band size: 41 kDa



    The MW is low because the recombinant fragment used as immunogen, rather than the full length protein, was used as positive control

References

ab58624 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab58624.
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