Overview

  • Product name

    Anti-HGFA Inhibitor 2 antibody
    See all HGFA Inhibitor 2 primary antibodies
  • Description

    Rabbit polyclonal to HGFA Inhibitor 2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human HGFA Inhibitor 2 aa 71-194.
    Sequence:

    CDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSE DHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNK NSYRSEEACMLRCFRQQENPPLPL


    Database link: O43291

  • Positive control

    • WB: Mouse lung tissue lysate. ICC/IF: A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab236907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/5000.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.
  • Tissue specificity

    Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.
  • Involvement in disease

    Defects in SPINT2 are the cause of diarrhea type 3 (DIAR3) [MIM:270420]; also known as congenital sodium diarrhea (CSD). DIAR3 is a rare, inherited diarrhea of infancy. A diagnosis of DIAR3 is made on the findings of a life-threatening secretory diarrhea, severe metabolic acidosis, and hyponatremia secondary to extraordinarily high fecal losses of sodium, with low or normal excretion of urinary sodium, in the absence of infectious, autoimmune, and endocrine causes.
  • Sequence similarities

    Contains 2 BPTI/Kunitz inhibitor domains.
  • Domain

    This inhibitor contains two inhibitory domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • AL024025 antibody
    • Bikunin, placental antibody
    • C76321 antibody
    • DIAR3 antibody
    • FLJ45571 antibody
    • HAI-2 antibody
    • HAI2 antibody
    • Hepatocyte growth factor activator inhibitor type 2 antibody
    • Kop antibody
    • Kunitz type protease inhibitor 2 antibody
    • Kunitz-type protease inhibitor 2 antibody
    • Kunitz-type serine protease inhibitor antibody
    • MGC72638 antibody
    • PB antibody
    • Placental bikunin antibody
    • Serine peptidase inhibitor Kunitz type 2 antibody
    • Serine protease inhibitor, Kunitz type, 2 antibody
    • SPINT2 antibody
    • SPIT2_HUMAN antibody
    see all

Images

  • A549 (human lung carcinoma cell line) cells stained for HGFA Inhibitor 2 (green) using ab236907 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody.

  • Anti-HGFA Inhibitor 2 antibody (ab236907) at 1/500 dilution + Mouse lung tissue lysate

    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution

References

ab236907 has not yet been referenced specifically in any publications.

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