Anti-HHV8 antibody [HHV8/3606] (ab267354)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HHV8 antibody [HHV8/3606] (ab267354)](https://www.abcam.com/ps/products/267/ab267354/Images/ab267354-357441-anti-hhv8-antibody-hhv8-3606-immunohistochemistry-kaposis-sarcoma.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HHV8 antibody [HHV8/3606] (ab267354)")
Key features and details
- Mouse monoclonal [HHV8/3606] to HHV8
- Suitable for: IHC-P
- Reacts with: Human herpesvirus
- Isotype: IgG1
Overview
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Product name
Anti-HHV8 antibody [HHV8/3606]
See all HHV8 primary antibodies -
Description
Mouse monoclonal [HHV8/3606] to HHV8 -
Host species
Mouse -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human herpesvirus -
Immunogen
Recombinant full length protein corresponding to Human herpesvirus HHV8. Recombinant protein corresponding to the latent nuclear antigen 1 molecule (product of the viral gene orf 73) of HHV8.
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Positive control
- IHC-P: Human Kaposi's sarcoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
Purity
Protein A/G purified -
Purification notes
Purified from bioreactor concentrate. -
Clonality
Monoclonal -
Clone number
HHV8/3606 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab267354 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 1 - 2 µg/ml.
Primary incucubation for 30 minutes at room temperature. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes. |
| Notes |
|---|
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IHC-P
Use a concentration of 1 - 2 µg/ml. Primary incucubation for 30 minutes at room temperature. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes. |
Target
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Relevance
HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma. -
Database links
- Entrez Gene: 935114 Human herpesvirus
- SwissProt: Q76SB0 Human herpesvirus
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Alternative names
- HHV 8 antibody
- Human Herpes Virus 8 antibody
- Human herpesvirus 8 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HHV8 antibody [HHV8/3606] (ab267354)
Formalin-fixed, paraffin-embedded human Kaposi's sarcoma tissue stained for HHV8 using ab267354 at 2 μg/ml in immunohistochemical analysis.
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab267354 has not yet been referenced specifically in any publications.
