Anti-HHV8 antibody [HHV8/3606] (ab267354)

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Overview

  • Product name

    Anti-HHV8 antibody [HHV8/3606]
    See all HHV8 primary antibodies

  • Description

    Mouse monoclonal [HHV8/3606] to HHV8

  • Host species

    Mouse

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human herpesvirus

  • Immunogen

    Recombinant full length protein corresponding to Human herpesvirus HHV8. Recombinant protein corresponding to the latent nuclear antigen 1 molecule (product of the viral gene orf 73) of HHV8.

  • Positive control

    • IHC-P: Human Kaposi's sarcoma tissue.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...

  • Purity

    Protein A/G purified

  • Purification notes

    Purified from bioreactor concentrate.

  • Clonality

    Monoclonal

  • Clone number

    HHV8/3606

  • Isotype

    IgG1

  • Light chain type

    kappa

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab267354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 - 2 µg/ml.

Primary incucubation for 30 minutes at room temperature.

Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes.

Target

  • Relevance

    HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.

  • Database links

    • Alternative names

      • HHV 8 antibody
      • Human Herpes Virus 8 antibody
      • Human herpesvirus 8 antibody
      • Kaposi's sarcoma associated herpes virus antibody
      • KSHV antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HHV8 antibody [HHV8/3606] (ab267354)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HHV8 antibody [HHV8/3606] (ab267354)

      Formalin-fixed, paraffin-embedded human Kaposi's sarcoma tissue stained for HHV8 using ab267354 at 2 μg/ml in immunohistochemical analysis.

      Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References

    Publishing research using ab267354? Please let us know so that we can cite the reference in this datasheet.

    ab267354 has not yet been referenced specifically in any publications.

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