Product nameAnti-HHV8 Cyclin antibody [94B]
DescriptionRat monoclonal [94B] to HHV8 Cyclin
Tested applicationsSuitable for: IP, WB, ICC/IFmore details
Species reactivityReacts with HHV8-encoded D type cyclin.
Recombinant fusion protein produced from a clone from HHV8.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab12208 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IP||Use at an assay dependent dilution.|
|WB||Use at an assay dependent dilution. Detects a band of approximately 30 kDa.|
|ICC/IF||Use at an assay dependent dilution.|
RelevanceHHV8 is associated with the develpment of Kaposi's Sarcoma and a number of B cell lymphomas in AIDS patients. HHV8 encodes a viral (v) cyclin homologous to cellular D type cyclins, a class of positive cell cycle regulators that are physiologically modulated by the p27(Kip1) cell cycle inhibitor.
- HHV 8 cyclin antibody
- HHV 8c antibody
- Human Herpesvirus 8 ORF72 antibody
This product has been referenced in:
- Nayar U et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest 127:2066-2080 (2017). Read more (PubMed: 28504647) »
- Sharma-Walia N et al. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol 88:2131-56 (2014). Read more (PubMed: 24335295) »