Anti-HIF-1 alpha antibody - ChIP Grade (ab2185)

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ab2185 has been referenced in 123 publications.

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  • Chen X  et al. Copper promotes the migration of bone marrow mesenchymal stem cells via Rnd3-dependent cytoskeleton remodeling. J Cell Physiol 235:221-231 (2020). PubMed: 31187497
  • Liu FY  et al. TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis. Cell Death Dis 10:480 (2019). PubMed: 31209243
  • Lee YS  et al. Hepatocyte-specific HIF-1a ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. Sci Adv 5:eaaw4176 (2019). PubMed: 31281892
  • Wang H  et al. Modulating effects of preconditioning exercise in the expression of ET-1 and BNP via HIF-1a in ischemically injured brain. Metab Brain Dis 34:1299-1311 (2019). PubMed: 31222402
  • Lu L  et al. Inhibitor of growth 4 (ING4) inhibits hypoxia-induced EMT by decreasing HIF-1a and snail in HK2 cells. Acta Histochem 121:695-703 (2019). PubMed: 31239073
  • Silberman A  et al. Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer. Cancer Res 79:518-533 (2019). PubMed: 30573518
  • Yang M  et al. Electro-Acupuncture Promotes Accumulation of Paclitaxel by Altering Tumor Microvasculature and Microenvironment in Breast Cancer of Mice. Front Oncol 9:576 (2019). PubMed: 31312613
  • Zhao W  et al. Effect of silencing HIF-1a gene on testicle spermatogenesis function in varicocele rats. Cell Tissue Res N/A:N/A (2019). PubMed: 31377879
  • Qin H  et al. PI3Kgamma Inhibitor Attenuates Immunosuppressive Effect of Poly(l-Glutamic Acid)-Combretastatin A4 Conjugate in Metastatic Breast Cancer. Adv Sci (Weinh) 6:1900327 (2019). PubMed: 31380170
  • Yang J  et al. LINK-A lncRNA activates HIF1a signaling and inhibits podocyte cell apoptosis in diabetic nephropathy. Exp Ther Med 18:119-124 (2019). PubMed: 31258644
  • Gao Y  et al. Dexmedetomidine protects hippocampal neurons against hypoxia/reoxygenation-induced apoptosis through activation HIF-1a/p53 signaling. Life Sci 232:116611 (2019). PubMed: 31260683
  • Jia Y  et al. Phosphorylation of 14-3-3? links YAP transcriptional activation to hypoxic glycolysis for tumorigenesis. Oncogenesis 8:31 (2019). PubMed: 31076568
  • Cortes E  et al. Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Rep 20:N/A (2019). PubMed: 30538116
  • Zakelj MN  et al. Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts. Oncol Rep 41:1658-1668 (2019). PubMed: 30628709
  • Lin P  et al. Magnesium lithospermate B improves renal hemodynamics and reduces renal oxygen consumption in 5/6th renal ablation/infarction rats. BMC Nephrol 20:49 (2019). PubMed: 30755161
  • Yang XL  et al. Optimal pressure in penile rehabilitation with a vacuum erection device: evidence based on a rat model. Asian J Androl N/A:N/A (2019). PubMed: 30924453
  • Zhang H  et al. LINK-A Long Non-Coding RNA (lncRNA) Participates in Metastasis of Ovarian Carcinoma and Upregulates Hypoxia-Inducible Factor 1 (HIF1a). Med Sci Monit 25:2221-2227 (2019). PubMed: 30912527
  • Dey P  et al. Green tea extract prevents obesity in male mice by alleviating gut dysbiosis in association with improved intestinal barrier function that limits endotoxin translocation and adipose inflammation. J Nutr Biochem 67:78-89 (2019). PubMed: 30856467
  • Zhang Z  et al. Overexpressed long noncoding RNA CPS1-IT alleviates pulmonary arterial hypertension in obstructive sleep apnea by reducing interleukin-1ß expression via HIF1 transcriptional activity. J Cell Physiol N/A:N/A (2019). PubMed: 30982984
  • Qin Y  et al. Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1a signaling pathway. EBioMedicine 38:25-36 (2018). PubMed: 30396856
  • Lai X  et al. Amelioration of diabetic nephropathy in db/db mice treated with tibetan medicine formula Siwei Jianghuang Decoction Powder extract. Sci Rep 8:16707 (2018). PubMed: 30420600
  • Xu Q  et al. Angiogenesis for tumor vascular normalization of Endostar on hepatoma 22 tumor-bearing mice is involved in the immune response. Oncol Lett 15:3437-3446 (2018). PubMed: 29467868
  • Simone L  et al. Aquaporin-1 inhibition reduces metastatic formation in a mouse model of melanoma. J Cell Mol Med 22:904-912 (2018). Mouse . PubMed: 29044946
  • Chen Z  et al. MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1a-mediated Warburg effect. Cell Death Dis 9:549 (2018). PubMed: 29748591
  • Pisani F  et al. Potential role of the methylation of VEGF gene promoter in response to hypoxia in oxygen-induced retinopathy: beneficial effect of the absence of AQP4. J Cell Mol Med 22:613-627 (2018). ChIP . PubMed: 28940930
  • Wang Y  et al. Effect of Repeated Injection of Iodixanol on Renal Function in Healthy Wistar Rats Using Functional MRI. Biomed Res Int 2018:7272485 (2018). PubMed: 29850557
  • Li F  et al. Detection of Hypoxia and HIF in Paraffin-Embedded Tumor Tissues. Methods Mol Biol 1742:277-282 (2018). PubMed: 29330808
  • Gruber S  et al. Radioprotective Effects of Dermatan Sulfate in a Preclinical Model of Oral Mucositis-Targeting Inflammation, Hypoxia and Junction Proteins without Stimulating Proliferation. Int J Mol Sci 19:N/A (2018). PubMed: 29882770
  • Han W  et al. Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats. Mediators Inflamm 2018:4798209 (2018). PubMed: 30050390
  • Deng W  et al. The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis. Cell Rep 24:366-378 (2018). PubMed: 29996098
  • Lambrechts D  et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat Med 24:1277-1289 (2018). PubMed: 29988129
  • van Wenum M  et al. Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines. J Cell Commun Signal 12:575-588 (2018). PubMed: 29399736
  • Lee KE  et al. Hif1a Deletion Limits Tissue Regeneration via Aberrant B Cell Accumulation in Experimental Pancreatitis. Cell Rep 23:3457-3464 (2018). PubMed: 29924990
  • Ferreira F  et al. Early redox activities modulate Xenopus tail regeneration. Nat Commun 9:4296 (2018). PubMed: 30327466
  • Serša I  et al. Multiparametric High-Resolution MRI as a Tool for Mapping of Hypoxic Level in Tumors. Technol Cancer Res Treat 17:1533033818797066 (2018). PubMed: 30176769
  • Sun B  et al. Qingchang Suppository Ameliorates Colonic Vascular Permeability in Dextran-Sulfate-Sodium-Induced Colitis. Front Pharmacol 9:1235 (2018). PubMed: 30429788
  • Li H  et al. Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1a/YAP signaling pathway. Int J Mol Med 42:3181-3192 (2018). PubMed: 30320354
  • Liu P  et al. Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1a/VEGF signalling. Sci Rep 7:12651 (2017). PubMed: 28978924
  • Prieto-Domínguez N  et al. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1a and hypoxia-mediated mitophagy. Oncotarget 8:91402-91414 (2017). PubMed: 29207653
  • Palsson-McDermott EM  et al. Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors. Front Immunol 8:1300 (2017). PubMed: 29081778
  • Kim JH  et al. Alpha lipoic acid attenuates radiation-induced oral mucositis in rats. Oncotarget 8:72739-72747 (2017). PubMed: 29069822
  • Zepeda-Orozco D  et al. EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. Physiol Rep 5:N/A (2017). PubMed: 28963126
  • Labiano S  et al. CD69 is a direct HIF-1a target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes. Oncoimmunology 6:e1283468 (2017). PubMed: 28507790
  • Rezaeian AH  et al. A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1a activation, tumorigenesis and metastasis. Nat Cell Biol 19:38-51 (2017). PubMed: 27918549
  • Gozal D  et al. Visceral White Adipose Tissue after Chronic Intermittent and Sustained Hypoxia in Mice. Am J Respir Cell Mol Biol 56:477-487 (2017). PubMed: 28107636
  • Savarin M  et al. Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response. Radiol Oncol 51:30-39 (2017). IHC-P ; Mouse . PubMed: 28265230
  • Piñeiro-Hermida S  et al. IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model. Sci Rep 7:4290 (2017). IHC-P ; Mouse . PubMed: 28655914
  • Li Z  et al. Ferulic Acid Improves Functional Recovery after Acute Spinal Cord Injury in Rats by Inducing Hypoxia to Inhibit microRNA-590 and Elevate Vascular Endothelial Growth Factor Expressions. Front Mol Neurosci 10:183 (2017). ChIP ; Rat . PubMed: 28642684
  • Juhasz A  et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem 292:7866-7887 (2017). IHC-P . PubMed: 28330872
  • Zhu G  et al. Long noncoding RNA HAS2-AS1 mediates hypoxia-induced invasiveness of oral squamous cell carcinoma. Mol Carcinog N/A:N/A (2017). Human . PubMed: 28485478
  • Lajko M  et al. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS One 11:e0166886 (2016). WB, IHC-P ; Mouse . PubMed: 27861592
  • Suyama K  et al. Circadian factors BMAL1 and RORa control HIF-1a transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget 7:23056-71 (2016). PubMed: 27049729
  • Shi Q  et al. Nitric oxide from brain microvascular endothelial cells may initiate the compensatory response to mild hypoxia of astrocytes in a hypoxia-inducible factor-1a dependent manner. Am J Transl Res 8:4735-4749 (2016). PubMed: 27904676
  • Hamanaka RB  et al. The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia. Cell Rep 15:451-459 (2016). PubMed: 27068470
  • Kwak JH  et al. HIF2a/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy. Oncotarget 7:43518-43533 (2016). WB . PubMed: 27270657
  • David V  et al. Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production. Kidney Int 89:135-46 (2016). WB . PubMed: 26535997
  • Lee KE  et al. Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia. Cancer Discov 6:256-69 (2016). IHC ; Mouse . PubMed: 26715642
  • Khaliullina H  et al. Nutrient-Deprived Retinal Progenitors Proliferate in Response to Hypoxia: Interaction of the HIF-1 and mTOR Pathway. J Dev Biol 4:N/A (2016). PubMed: 27280081
  • Shi W  et al. Transplantation of RADA16-BDNF peptide scaffold with human umbilical cord mesenchymal stem cells forced with CXCR4 and activated astrocytes for repair of traumatic brain injury. Acta Biomater 45:247-261 (2016). WB ; Rat . PubMed: 27592818
  • Chen Y  et al. MicroRNA-18b inhibits the growth of malignant melanoma via inhibition of HIF-1a-mediated glycolysis. Oncol Rep 36:471-9 (2016). WB . PubMed: 27220837
  • Yamaguchi R  et al. HIF-1-Dependent IL-6 Activation in Articular Chondrocytes Initiating Synovitis in Femoral Head Ischemic Osteonecrosis. J Bone Joint Surg Am 98:1122-31 (2016). PubMed: 27385686
  • Li CT  et al. Notch signaling represses hypoxia-inducible factor-1a-induced activation of Wnt/ß-catenin signaling in osteoblasts under cobalt-mimicked hypoxia. Mol Med Rep 14:689-96 (2016). WB ; Mouse . PubMed: 27220406
  • Thuringer D  et al. Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions. Oncotarget 7:73925-73934 (2016). Human . PubMed: 27661112
  • Campos D  et al. Radiation Promptly Alters Cancer Live Cell Metabolic Fluxes: An In Vitro Demonstration. Radiat Res 185:496-504 (2016). PubMed: 27128739
  • Erb MJ  et al. Extracellular Signal-Regulated Kinase 2 and CHOP Restrict the Expression of the Growth Arrest-Specific p20K Lipocalin Gene to G0. Mol Cell Biol 36:2890-2902 (2016). PubMed: 27601586
  • Bayin NS  et al. GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth. Oncogenesis 5:e263 (2016). PubMed: 27775701
  • Babapoor-Farrokhran S  et al. Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy. Proc Natl Acad Sci U S A 112:E3030-9 (2015). PubMed: 26039997
  • Hu B  et al. Fatty acid binding protein-4 (FABP4) is a hypoxia inducible gene that sensitizes mice to liver ischemia/reperfusion injury. J Hepatol 63:855-62 (2015). PubMed: 26070408
  • Palsson-McDermott EM  et al. Pyruvate kinase M2 regulates Hif-1a activity and IL-1ß induction and is a critical determinant of the warburg effect in LPS-activated macrophages. Cell Metab 21:65-80 (2015). PubMed: 25565206
  • Wang F  et al. Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1a. J Cell Mol Med 19:1400-9 (2015). ChIP . PubMed: 25781495
  • Wong WJ  et al. Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol 135:454-461 (2015). IHC . PubMed: 24999590
  • Shen G  et al. Adipose differentiation-related protein is not involved in hypoxia inducible factor-1-induced lipid accumulation under hypoxia. Mol Med Rep 12:8055-61 (2015). ChIP . PubMed: 26498183
  • Joseph JV  et al. Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1a-ZEB1 axis. Cancer Lett 359:107-16 (2015). PubMed: 25592037
  • Chourasia AH  et al. Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis. EMBO Rep 16:1145-63 (2015). WB, IHC ; Mouse . PubMed: 26232272
  • Paolillo R  et al. Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells. PLoS One 10:e0126968 (2015). ChIP ; Human . PubMed: 25961573
  • Kumar P  et al. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS One 10:e0123725 (2015). WB, ChIP ; Human . PubMed: 25974097
  • Lee JG  et al. Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions. Respir Res 16:138 (2015). IHC ; Human . PubMed: 26553068
  • de Bruin A  et al. Genome-wide analysis reveals NRP1 as a direct HIF1a-E2F7 target in the regulation of motorneuron guidance in vivo. Nucleic Acids Res : (2015). ChIP ; Human . PubMed: 26681691
  • Vorrink SU  et al. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicol Appl Pharmacol 274:408-16 (2014). PubMed: 24355420
  • Vorrink SU  et al. PCB 126 perturbs hypoxia-induced HIF-1a activity and glucose consumption in human HepG2 cells. Exp Toxicol Pathol 66:377-82 (2014). PubMed: 24916446
  • Metheni M  et al. The level of H2O2 type oxidative stress regulates virulence of Theileria-transformed leukocytes. Cell Microbiol 16:269-79 (2014). WB . PubMed: 24112286
  • Zecchini V  et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J 33:1365-82 (2014). PubMed: 24837709
  • Rosik L  et al. Limited efficacy of specific HDAC6 inhibition in urothelial cancer cells. Cancer Biol Ther 15:742-57 (2014). PubMed: 24618845
  • Bakirtzi K  et al. The neurotensin-HIF-1a-VEGFa axis orchestrates hypoxia, colonic inflammation, and intestinal angiogenesis. Am J Pathol 184:3405-14 (2014). PubMed: 25307345
  • Zheng X  et al. Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proc Natl Acad Sci U S A 111:2560-5 (2014). ChIP . PubMed: 24550283
  • Cheverud JM  et al. Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Heredity (Edinb) 112:508-18 (2014). Mouse . PubMed: 24569637
  • Aesoy R  et al. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Mol Cancer 13:54 (2014). WB ; Human . PubMed: 24618291
  • Storti F  et al. A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Haematologica 99:e45-8 (2014). ChIP . PubMed: 24510339
  • Asnaghi L  et al. Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation. PLoS One 9:e105372 (2014). IHC-Fr ; Human . PubMed: 25166211
  • Paatero I  et al. Hypoxia-inducible factor-1a induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem 289:22459-69 (2014). WB ; Mouse . PubMed: 24966332
  • Vavilala DT  et al. Evaluation of anti-HIF and anti-angiogenic properties of honokiol for the treatment of ocular neovascular diseases. PLoS One 9:e113717 (2014). WB, ChIP ; Human . PubMed: 25422886
  • Chen X  et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway. Nature 508:103-7 (2014). ChIP ; Human . PubMed: 24670641
  • Gómez-Maldonado L  et al. EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination. Oncogene 0: (2014). PubMed: 25023702
  • Biswas S  et al. Insulin regulates hypoxia-inducible factor-1a transcription by reactive oxygen species sensitive activation of Sp1 in 3T3-L1 preadipocyte. PLoS One 8:e62128 (2013). WB ; Mouse . PubMed: 23626778
  • Yi T  et al. Hypoxia-inducible factor-1a (HIF-1a) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J Biol Chem 288:18732-42 (2013). ChIP ; Human . PubMed: 23667251
  • Xin X  et al. Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4. Proc Natl Acad Sci U S A 110:E3425-34 (2013). WB ; Mouse . PubMed: 23959876
  • Ronkainen VP  et al. Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. Cardiovasc Res N/A:N/A (2013). PubMed: 24095869
  • Rajendran R  et al. Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer. Int J Oncol 42:1961-72 (2013). PubMed: 23591450
  • Taniguchi CM  et al. Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Nat Med 19:1325-30 (2013). PubMed: 24037093
  • Villar D  et al. Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions. PLoS One 7:e45708 (2012). PubMed: 23029193
  • Shen GM  et al. Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia. Biochem J 441:675-83 (2012). PubMed: 21970364
  • Weijts BG  et al. E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J 31:3871-84 (2012). ChIP . PubMed: 22903062
  • Doublier S  et al. HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast. BMC Cancer 12:4 (2012). IHC-P ; Human . PubMed: 22217342
  • Zhou W  et al. HIF1a induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J : (2012). WB ; Mouse . PubMed: 22446391
  • Hari Kishore A  et al. Hypoxia and PGE(2) regulate MiTF-CX during cervical ripening. Mol Endocrinol 26:2031-45 (2012). PubMed: 23144021
  • Stiehl DP  et al. Non-canonical HIF-2a function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene 31:2283-97 (2012). PubMed: 21927022
  • Wollenick K  et al. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res 40:1928-43 (2012). ChIP . PubMed: 22075993
  • Hu J  et al. Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes. Mol Cancer Res 9:1520-36 (2011). ChIP ; Human . PubMed: 21984181
  • Jensen KS  et al. FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function. EMBO J 30:4554-70 (2011). ChIP . PubMed: 21915097
  • Gaber T  et al. Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1alpha function and differentially influences human CD4+ T cell proliferation under hypoxia. J Immunol 186:764-74 (2011). ChIP ; Human . PubMed: 21169549
  • Vanhorebeek I  et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 96:E633-45 (2011). WB ; Human . PubMed: 21270330
  • Satoh M  et al. Mitochondrial damage-induced impairment of angiogenesis in the aging rat kidney. Lab Invest 91:190-202 (2011). PubMed: 20921951
  • Ortiz-Barahona A  et al. Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res : (2010). ChIP ; Human . PubMed: 20061373
  • Pescador N  et al. Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. PLoS One 5:e9644 (2010). ChIP ; Mouse . PubMed: 20300197
  • Acosta-Iborra B  et al. Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1alpha transcription factor. J Immunol 182:3155-64 (2009). ChIP ; Mouse . PubMed: 19234213
  • Piña-Oviedo S  et al. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol 118:235-47 (2009). ChIP ; Human . PubMed: 19360424
  • Zhang Z  et al. MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle 8:2756-68 (2009). ChIP ; Human . PubMed: 19652553
  • Beyer S  et al. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J Biol Chem 283:36542-52 (2008). ChIP ; Human . PubMed: 18984585
  • Sahlgren C  et al. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci U S A 105:6392-7 (2008). ChIP ; Human . PubMed: 18427106
  • Belaidi E  et al. Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat. Am J Physiol Heart Circ Physiol 294:H901-8 (2008). ChIP ; Rat . PubMed: 18083903
  • Kulshreshtha R  et al. A microRNA signature of hypoxia. Mol Cell Biol 27:1859-67 (2007). ChIP ; Human . PubMed: 17194750
  • Anderson CJ  et al. Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms. Oncogene 25:61-9 (2006). ChIP ; Human . PubMed: 16170363
  • Pescador N  et al. Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene. Biochem J 390:189-97 (2005). ChIP ; Human . PubMed: 15823097

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