Overview

  • Product name

  • Description

    Rabbit polyclonal to HIPK1
  • Host species

    Rabbit
  • Specificity

    ab198802 detects endogenous levels of total HIPK1 protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human HIPK1 (internal sequence). NP_938009.
    Database link: Q86Z02

  • Positive control

    • Human thyroid cancer tissue and Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function

    May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
  • Tissue specificity

    Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Autophosphorylated. Phosphorylated and activated by JNK1.
  • Cellular localization

    Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • Database links

  • Alternative names

    • Hipk 1 antibody
    • Hipk1 antibody
    • HIPK1_HUMAN antibody
    • Homeodomain interacting protein kinase 1 antibody
    • Homeodomain interacting protein kinase 1 like protein antibody
    • Homeodomain-interacting protein kinase 1 antibody
    • Myak antibody
    • Nbak 2 antibody
    • Nbak2 antibody
    • Nuclear body associated kinase 2 antibody
    • Nuclear body associated kinase 2b antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling HIPK1 with ab198802 at 1/25 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling HIPK1 with ab198802 at 1/25 dilution.

References

ab198802 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198802.
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