Overview

  • Product name

    Anti-Histone H1 antibody [HH1/1784R]
    See all Histone H1 primary antibodies
  • Description

    Rabbit monoclonal [HH1/1784R] to Histone H1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human Histone H1.

  • Positive control

    • Human pancreas tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab218418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
  • Tissue specificity

    Oocyte-specific.
  • Sequence similarities

    Belongs to the histone H1/H5 family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
  • Cellular localization

    Cytoplasm. Nucleus. Chromosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • dJ221C16.2 antibody
    • dJ221C16.5 antibody
    • DmeH1 antibody
    • H1 0 histone antibody
    • H1 antibody
    • H1 histone family member 0 antibody
    • H1 histone family member 1 antibody
    • H1 histone family member 3 antibody
    • H1 histone family member 5 antibody
    • H1 histone family member N testis specific antibody
    • H1 histone family member O oocyte specific antibody
    • H1 histone family member X antibody
    • H1(0) antibody
    • H1.1 antibody
    • H1.2 antibody
    • H1.3 antibody
    • H1.4 antibody
    • H1.5 antibody
    • H10 antibody
    • H1A antibody
    • H1f0 antibody
    • H1F0 protein antibody
    • H1F1 antibody
    • H1F2 antibody
    • H1F3 antibody
    • H1F4 antibody
    • H1F5 antibody
    • H1FNT antibody
    • H1FOO antibody
    • H1FOO protein antibody
    • H1FOO_HUMAN antibody
    • H1FT antibody
    • H1FV antibody
    • H1FX antibody
    • H1oo antibody
    • H1t antibody
    • H1T2 antibody
    • H1X antibody
    • HANP1 antibody
    • His1 antibody
    • HisC antibody
    • HIST1 antibody
    • HIST1H1A antibody
    • HIST1H1B antibody
    • HIST1H1C antibody
    • HIST1H1D antibody
    • HIST1H1E antibody
    • HIST1H1T antibody
    • Histone 1 H1a antibody
    • Histone 1 H1b antibody
    • Histone 1 H1c antibody
    • Histone 1 H1d antibody
    • Histone 1 H1e antibody
    • Histone 1 H1t antibody
    • Histone antibody
    • Histone H1' antibody
    • Histone H1.0 antibody
    • Histone H1.1 antibody
    • Histone H1.2 antibody
    • Histone H1.3 antibody
    • Histone H1.4 antibody
    • Histone H1.5 antibody
    • Histone H1oo antibody
    • Histone H1x antibody
    • MGC116819 antibody
    • MGC126630 antibody
    • MGC126632 antibody
    • MGC126642 antibody
    • MGC138176 antibody
    • MGC138345 antibody
    • MGC15959 antibody
    • MGC3992 antibody
    • MGC50807 antibody
    • MGC5241 antibody
    • MGC8350 antibody
    • Oocyte specific histone H1 antibody
    • Oocyte specific linker histone H1 antibody
    • Oocyte-specific histone H1 antibody
    • Oocyte-specific linker histone H1 antibody
    • osH1 antibody
    • Testicular H1 histone antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human pancreas tissue labeling Histone H1 using ab218418 at 1 µg/ml.

References

ab218418 has not yet been referenced specifically in any publications.

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