Overview

  • Product name

    Anti-Histone H1t2 antibody
    See all Histone H1t2 primary antibodies
  • Description

    Rabbit polyclonal to Histone H1t2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human Histone H1t2 aa 1-164.

  • Positive control

    • MCF7 whole cell lysate
  • General notes

    Store undiluted.

Properties

Applications

Our Abpromise guarantee covers the use of ab127045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.

Target

  • Function

    Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1.
  • Tissue specificity

    Testis-specific.
  • Sequence similarities

    Belongs to the histone H1/H5 family.
  • Cellular localization

    Nucleus. Chromosome. In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole.
  • Information by UniProt
  • Database links

  • Alternative names

    • H1 histone family member N testis specific antibody
    • H1FNT antibody
    • H1FNT_HUMAN antibody
    • H1T2 antibody
    • HANP1 antibody
    • Haploid germ cell-specific nuclear protein 1 antibody
    • Histone H1t2 antibody
    • Testis-specific H1 histone antibody
    see all

Images

  • Anti-Histone H1t2 antibody (ab127045) at 1/2000 dilution + MCF7 whole cell lysate at 30 µg

    Predicted band size: 28 kDa



    12% SDS-PAGE

References

ab127045 has not yet been referenced specifically in any publications.

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