Overview

  • Product name

    Histone H4 (acetyl K16) Quantification Kit (Fluorometric)
    See all Histone H4 kits
  • Detection method

    Fluorescent
  • Sample type

    Tissue, Adherent cells, Suspension cells
  • Sensitivity

    0.4 ng/well
  • Range

    20 ng/well - 5000 ng/well
  • Assay time

    2h 30m
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Mammals
  • Product overview

    Acetylation of histones such histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H4 actylation. Histone H4 (acetyl K16) reflects the hyperacetylated stated in histone H4 and strongly correlates with active state of genes. H4 (acetyl K16) is also related to euchromatin and DNA repair, while hypoacetylation of H4(K16) is commonly found in human tumors.

    Abcam's Histone H4 (acetyl K16) Quantification Kit (Fluorometric) (ab115121) allows the experimenter to measure global acetylation of histone H4K16 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H4K16 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • Platform

    Microplate reader

Properties

Protocols

References

ab115121 has not yet been referenced specifically in any publications.

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