Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119)
- Datasheet
- Specific References
- Protocols
Overview
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Product nameHistone H4 (acetyl K8) Quantification Kit (Fluorometric)
See all Histone H4 (K8 acetylation) kits -
Sensitivity0.4 ng/well
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Range20 ng/well - 5000 ng/well
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Assay time2h 30m
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Species reactivityReacts with: Mouse, Human
Predicted to work with: Mammals
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Product overview
Acetylation of histones such histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H4 actylation. Histone H4 (acetyl K8) reflects the hyperacetylated stated in histone H4 and strongly correlates with active state of genes. H4 (acetyl K8) is related to DNA repair and increased H4 (acetyl K8) has been observed in cancer and inflammatory diseases.
Abcam's Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119) allows the experimenter to measure global acetylation of histone H4K8 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H4K8 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.
Properties
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Storage instructionsPlease refer to protocols.
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Components Identifier 48 tests 96 tests 10X Wash Buffer 1 x 10ml 1 x 20ml 8-Well Sample Strips (with Frame) 6 units 9 units 8-Well Standard Control Strips Green Ringed 2 units 3 units Antibody Buffer 1 x 6ml 1 x 12ml Detecting Antibody, 1 mg/mL 1 x 5µl 1 x 10µl Fluoro Developer 1 x 12µl 1 x 24µl Fluoro Dilution 1 x 4ml 1 x 8ml Fluoro Enhancer 1 x 12µl 1 x 24µl Signal Enhancer 1 x 120µl 1 x 240µl Signal Report Solution 1 x 5µl 1 x 10µl Standard Control, 100 µg/mL 1 x 10µl 1 x 20µl -
Research areas
Associated products
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Related Products
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- Histone H4 (acetyl K16) Quantification Kit (Fluorometric) (ab115121)
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Protocols
References
ab115119 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"