Key features and details
- Goat polyclonal to HIV gp160
- Suitable for: WB, ELISA
- Isotype: IgG
Product nameAnti-HIV gp160 antibody
DescriptionGoat polyclonal to HIV gp160
Specificityab117122 reacts strongly with gp41, gp120 and gp160 in western blot assays. ELISA based peptide mapping studies have confirmed high titer reactivity to HIV MN env peptide in the following regions: (6332)IEPLGVAPTKAKRRV, (6360) CTTTVPWNASWSNKS and moderate activity to multiple other regions on the env polypeptide.
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Other species
Other Immunogen Type corresponding to HIV gp160. ab117122 was produced using a cocktail of three recombinant antigens: gp41, gp120, and gp41/120 hybrid.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 0.88% Sodium chloride
pH range 6.0-7.0
Concentration information loading...
PurityIon Exchange Chromatography
Our Abpromise guarantee covers the use of ab117122 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Predicted molecular weight: 97 kDa.|
|ELISA||Use at an assay dependent dilution.|
RelevanceEndoproteolytic processing of human immunodeficiency virus type 1 (HIV1) gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Cellular localizationCell Membrane
- env antibody
- Env polyprotein antibody
- Envelope glycoprotein gp160 antibody
ab117122 has not yet been referenced specifically in any publications.