Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab20460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/1000.
WB 1/50 - 1/100. The antibody was tested on HIV-1 strips. More concentrated antibody might be necessary for other sample formats for WB.

Target

  • Relevance
    HIV is a highly variable virus which mutates very readily. This means there are many different strains of HIV, even within the body of a single infected person. The strains of HIV1 can be classified into three groups : the "major" group M, the "outlier" group O and the "new" group N. These three groups may represent three separate introductions of simian immunodeficiency virus into humans. Group O appears to be restricted to West-Central Africa and group N, discovered in 1998 in Cameroon, is extremely rare. More than 90% of HIV1 infections belong to HIV1 group M.
  • Alternative names
    • HIV 1 antibody
    • HTLV3 antibody
    • Human Immunodeficiency Virus 1 antibody

References

ab20460 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-4 of 4 Abreviews or Q&A

Answer

Thank you for your enquiry. Further to contact with the source of this antibody I have determined that this antibody has been tested using indirect immunofluorescence. Reactivity against the HIV-1 proteins p17, p24, p53, p64, gp120, gp160 and gp41 was tested using Western blotting against purified forms of the protein. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

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Answer

Thank you for your enquiry. Ab20460 will recognize gp41. We do not have any information about reactivity to reverse transcriptase, integrase, or protease. Please let me know if you need further information,

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Answer

This statement refers to uninfected cells. Goat anti HIV-1 does not react with uninfected T4+ human lymphocytes.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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