Key features and details
- Rabbit polyclonal to HIV1 gp120
- Suitable for: WB
- Isotype: IgG
Product nameAnti-HIV1 gp120 antibody
See all HIV1 gp120 primary antibodies
DescriptionRabbit polyclonal to HIV1 gp120
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Other species
16 amino acid peptide representing the major HIV1 consensus sequence near the N terminal region of V1/V2 loop (GenBank accession no. AAT67551).
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106578 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 120 kDa.|
RelevanceHIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Cellular localizationEnvelope surface glycoprotein.
- Glycoprotein 120 antibody
- gp120 antibody
- SU antibody
- Surface protein antibody
Western Blot of HIV1 gp120 (5ng) labeling HIV1 gp120 with Anti-HIV1 gp120 antibody (ab106578) at 1µg/ml.
Lane 1 : Anti-HIV1 gp120 antibody (ab106578) at 1 µg/ml
Lane 2 : Anti-HIV1 gp120 antibody (ab106578) at 2 µg/ml
All lanes : gp120 protein
Lysates/proteins at 1 µg per lane.
Predicted band size: 120 kDa
ab106578 has not yet been referenced specifically in any publications.