Product nameAnti-HIV1 gp120 antibody (Biotin)
See all HIV1 gp120 primary antibodies
DescriptionGoat polyclonal to HIV1 gp120 (Biotin)
Tested applicationsSuitable for: WB, ELISA, IHC-Fr, ICC/IFmore details
Species reactivityReacts with: Species independent
Full length native protein (purified) corresponding to HIV1 gp120. Purified native gp120 from strain IIIB.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
Purification notesPurified IgG conjugated to Biotin.
Our Abpromise guarantee covers the use of ab53937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution.|
|ELISA||Use at an assay dependent dilution.|
|IHC-Fr||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution.|
RelevanceHIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Cellular localizationEnvelope surface glycoprotein.
- Glycoprotein 120 antibody
- gp120 antibody
- SU antibody
- Surface protein antibody
This product has been referenced in:
- Beraud C et al. Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-?B activation. Virol J 15:35 (2018). Read more (PubMed: 29454367) »
- Safavieh M et al. Paper microchip with a graphene-modified silver nano-composite electrode for electrical sensing of microbial pathogens. Nanoscale 9:1852-1861 (2017). Read more (PubMed: 27845796) »