• Product name
    Anti-HIV1 gp120 antibody (Biotin)
    See all HIV1 gp120 primary antibodies
  • Description
    Goat polyclonal to HIV1 gp120 (Biotin)
  • Host species
  • Conjugation
  • Specificity
    ab53937 is specific for gp120. It does not cross react with human T or B cells, human or bovine sera.
  • Tested applications
    Suitable for: WB, ELISA, IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with Human Immunodeficiency Virus 1 Gp120.
  • Immunogen

    Full length native protein (purified) corresponding to HIV1 gp120. Purified native gp120 from strain IIIB.



Our Abpromise guarantee covers the use of ab53937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.


  • Relevance
    HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
  • Cellular localization
    Envelope surface glycoprotein.
  • Alternative names
    • Glycoprotein 120 antibody
    • gp120 antibody
    • SU antibody
    • Surface protein antibody


This product has been referenced in:
  • Beraud C  et al. Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-?B activation. Virol J 15:35 (2018). Read more (PubMed: 29454367) »
  • Safavieh M  et al. Paper microchip with a graphene-modified silver nano-composite electrode for electrical sensing of microbial pathogens. Nanoscale 9:1852-1861 (2017). Read more (PubMed: 27845796) »

See all 9 Publications for this product

Customer reviews and Q&As

Vielen Dank für Ihre Anfrage.

Leider muss ich Ihnen mitteilen, dass dies nicht zu unseren Standartmethoden gehört, wenn wir einen Antikörper entwickeln und charakterisieren.

Was Sie allerdings machen könnten, wenn ...

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Thank you for contacting us.

I am sorry that this antibody did not perform as stated on the datasheet. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact ou...

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Thank you for your enquiry and your interest in our products.
This antibody has not been tested against the HXB2 or JRFL strains yet. However, given the polyclonal nature of the antibody, there is a good chance it would react to these strains but ...

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Gracias por contactarnos.

Anti-HIV1 p24 [39/5.4A] (ab9071) tiene un precio de 370€ y se encuentra actualmente en stock, por lo que si lo pedís esta tarde o mañana (martes 12) a lo largo del día (antes de las 17 horas...

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Thank you for contacting us. This product is raised from purified native gp120 from strain IIIB. We have not sequenced the native protein used to raise this antibody. We have searched, and unfortunately, the gp120 sequence has not been submitted f...

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Thank you for contacting us.

Here is the sequence you requested:

gp120 [Human immunodeficiency virus 1]
GenBank: AAF69493.1
GenPept Graphics

>gi|7769646|gb|AAF69493.1|AF236860_1 gp120 [H...

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Thank you for your reply. To reduce the non-specific binding of your secondary antibody, you could: - Change your blocking agent, to either 5% non fat dried milk or 5% BSA. - Lower the concentration of the secondary antibody that you are using. - Add b...

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Thank you for contacting Abcam. I just want to make sure that I understand your negative control correctly; for your negative control, you added the secondary antibody only (no primary antibody) and that is the lane labeled 'gp120 negative'. Is that co...

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Thank you for your enquiry. These 4 products (ab21179, ab20105, ab20262, ab20008) were produced from the same goat antiserum. Catalog ab21179 is the purified antibody. The purified antibody is then labeled to produce the other catalog numbers: Bio...

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