HRP Anti-HIV1 gp120 antibody (ab53840)
Key features and details
- HRP Goat polyclonal to HIV1 gp120
- Suitable for: WB, ELISA, IHC-Fr
- Reacts with: Human immunodeficiency virus
- Conjugation: HRP
- Isotype: IgG
Overview
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Product name
HRP Anti-HIV1 gp120 antibody
See all HIV1 gp120 primary antibodies -
Description
HRP Goat polyclonal to HIV1 gp120 -
Host species
Goat -
Conjugation
HRP -
Specificity
Gp120 is the predominant band in WB. -
Tested applications
Suitable for: WB, ELISA, IHC-Frmore details -
Species reactivity
Reacts with: Human immunodeficiency virus -
Immunogen
Full length native protein, from strain IIIB.
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General notes
Estimated molar HRP:IgG substitution is 2-3. Free enzyme is absent.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: 1% BSA, PBS -
Concentration information loading...
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Purification notes
>95% -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Related Products
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Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53840 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
1/20 - 1/200.
|
ELISA |
1/200 - 1/1000.
|
|
IHC-Fr |
1/20 - 1/200.
|
Notes |
---|
WB
1/20 - 1/200. |
ELISA
1/200 - 1/1000. |
IHC-Fr
1/20 - 1/200. |
Target
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Relevance
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response. -
Cellular localization
Envelope surface glycoprotein. -
Database links
- Entrez Gene: 155971 Human immunodeficiency virus
- GenBank: AAG28611 Human immunodeficiency virus
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Alternative names
- Glycoprotein 120 antibody
- gp120 antibody
- SU antibody
- Surface protein antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab53840 has been referenced in 1 publication.
- Grimm SK et al. Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies. PLoS One 10:e0117227 (2015). WB . PubMed: 25688555