Key features and details
- Mouse monoclonal [1D4] to HIV1 gp41
- Suitable for: ELISA, WB
- Isotype: IgG1
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Concentration information loading...
PurityProtein G purified
Purification notesAmmonium sulphate precipitate
Our Abpromise guarantee covers the use of ab18633 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
- Env antibody
- Glycoprotein 41 antibody
- gp41 antibody
ab18633 has not yet been referenced specifically in any publications.