Overview

  • Product name
    Anti-HIV1 gp41 antibody [1D4]
    See all HIV1 gp41 primary antibodies
  • Description
    Mouse monoclonal [1D4] to HIV1 gp41
  • Host species
    Mouse
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with HIV1 Not yet tested in other species.
  • Immunogen

    Recombinant fragment (strain IIIB).

Properties

Applications

Our Abpromise guarantee covers the use of ab18633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/1000.

Target

  • Relevance
    gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
  • Alternative names
    • Env antibody
    • Glycoprotein 41 antibody
    • gp41 antibody
    • Human Immunodeficiency Virus 1 antibody
    • TM antibody
    • Transmembrane protein antibody
    see all

References

ab18633 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-4 of 4 Abreviews or Q&A

Question
Answer

DISCOUNT CODE: ***
Expiration date: December 2nd, 2012

I am very pleased to hear you would like to accept our offer and test ab18633 in ICC. This code will give you: 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for ICCand include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active.
For more information on how to submit an Abreview, please visit the site: https://www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.

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Question
Answer

Thank you for your patience in this matter. I have received replies from the originators of ab9065 and ab18633. In regards to ab9065, this antibody was produced to the HIV-1 B-3 strain and its' reactivity with the LAV strain has not been tested in WB. Regarding ab18633, this antibody was raised to the HIV IIIB strain and its' reactivity with the LAV strain has not been determined. Please do not hesitate to contact us again if you have further questions.

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Question
Answer

Thank you for your enquiry. Ab18633 was raised to HIV-1 env gp41 antigen (recombinant) a.a 466 to a.a 753 of the HIV-1 env region 32 kDa. Unfortunately, the epitope was not mapped. I hope this information helps. Plase do not hesitate to contact us if you need anything further.

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Answer

Thank you for your enquiry. I have been in touch with the source of these HIV gp120 and gp41 antibodies and I have determine that unfortunately none of them have been tested against the HIV strain YU2. I can tell you that ab18633 is predicted, based on broad reactivity to react with HIV strain YU2. I am sorry that I cannot be of more assistance on this occasion.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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