Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS
Concentration information loading...
PurityIon Exchange Chromatography
Purification notesAb20890 is purified by sodium sulfate precipitation and ion-exchange chromatography. The antiserum has not been adsorbed to remove anti-beta-galactosidase activity.
Our Abpromise guarantee covers the use of ab20890 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100. Predicted molecular weight: 41 kDa. Major band seen in WB at 41kDa and a minor band at 20kDa. Dilution optimised using Chromogenic detection.|
Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
- Env antibody
- Glycoprotein 41 antibody
- gp41 antibody
ab20890 has not yet been referenced specifically in any publications.