Key features and details
- Mouse monoclonal  to HIV1 Rev
- Suitable for: ELISA, WB, Radioimmunoprecipitation
- Isotype: IgG1
Product nameAnti-HIV1 Rev antibody 
See all HIV1 Rev primary antibodies
DescriptionMouse monoclonal  to HIV1 Rev
SpecificityHIV1 Rev regulatory protein.
Tested applicationsSuitable for: ELISA, WB, Radioimmunoprecipitationmore details
Species reactivityReacts with: Other species
To produce this antibody the recombinant Rev (strain BRU) has been used as immunogen. The peptide sequences were not derived from particular strains of HIV1, but were designed as (artificial) B-clade (strain) consensus sequences. Sequences in Swiss prot belong to particular HIV1 strains. For epitope mapping synthetic peptides were used.
EpitopeEpitope mapped to aa34-40
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab25871 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 13 kDa.|
|Radioimmunoprecipitation||Use at an assay dependent dilution.|
RelevanceHIV1 expresses the trans-activator protein Rev which is required for virus growth as it promotes the localisation and expression of viral RNA in the cytoplasm. Rev is a model experimental system for studying nuclear transport. The HIV1 Rev protein as viral protein is expressed early in the virus life cycle and thus may be important targets for the immune control of HIV1 infection.
- Human immunodeficiency virus 1 Rev antibody
- Protein Rev antibody
- Regulator of expression of viral proteins antibody
- Rev antibody
ab25871 has been referenced in 2 publications.
- Nomaguchi M et al. Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels. J Virol 90:4563-4578 (2016). PubMed: 26912631
- Nomaguchi M et al. Natural single-nucleotide polymorphisms in the 3' region of the hiv-1 pol gene modulate viral replication ability. J Virol 88:4145-60 (2014). WB . PubMed: 24478432