Product nameAnti-HIV1 tat antibody (Biotin)
See all HIV1 tat primary antibodies
DescriptionRabbit polyclonal to HIV1 tat (Biotin)
Tested applicationsSuitable for: WB, ELISA, Flow Cytmore details
Species reactivityReacts with: Other species
Recombinant full length protein expressed in E. coli
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: None
Constituents: 0.05% Glycerol, PBS, pH 7.4
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab43015 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt: 1/200. Use Streptavidin-FITC conjugated detection reagent.
WB: 1/1000. Predicted molecular weight: 14 kDa. Use Streptavidin (HRP) conjugated detection reagent.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Cellular localizationNuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
- p14 antibody
- Protein Tat antibody
- Transactivating regulatory protein antibody
This product has been referenced in:
- Dickens AM et al. Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging. Sci Rep 7:7748 (2017). ELISA . Read more (PubMed: 28798382) »
- Johnson TP et al. Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein. Proc Natl Acad Sci U S A 110:13588-93 (2013). Read more (PubMed: 23898208) »