This product reacts in ELISA and WB with HIV1 Tat of the HxB2, BH10, IIIB, HAN strains.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
Protein Tat antibody
Transactivating regulatory protein antibody
Western blot - Anti-HIV1 tat antibody [N1] (ab42360)
Lane 1 : Anti-HIV1 tat antibody [N1] (ab42360)
Lane 1 : Recominant HIV1 Tat (B subtype) Lane 2 : Protein size marker