Key features and details
- Mouse monoclonal [N1] to HIV1 tat
- Suitable for: ELISA, WB
- Isotype: IgG3
Product nameAnti-HIV1 tat antibody [N1]
See all HIV1 tat primary antibodies
DescriptionMouse monoclonal [N1] to HIV1 tat
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Other species
Recombinant full length protein (Human)
EpitopeMapped to amino acids 71-81 (KQPASQPRGDP) - B subtype aa consensus).
General notesAlso known as clone 02-012.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Concentration information loading...
PurityProtein G purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab42360 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/5000. Predicted molecular weight: 59 kDa.
This product reacts in ELISA and WB with HIV1 Tat of the HxB2, BH10, IIIB, HAN strains.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Cellular localizationNuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
- p14 antibody
- Protein Tat antibody
- Transactivating regulatory protein antibody
ab42360 has not yet been referenced specifically in any publications.