Anti-HIV2 Nef antibody [4B5] (ab22626)
Key features and details
- Rat monoclonal [4B5] to HIV2 Nef
- Suitable for: WB, IP
- Isotype: IgG1
Overview
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Product name
Anti-HIV2 Nef antibody [4B5] -
Description
Rat monoclonal [4B5] to HIV2 Nef -
Host species
Rat -
Tested applications
Suitable for: WB, IPmore details -
Species reactivity
Reacts with: Other species -
Immunogen
Fusion protein: TrpE-Fusion protein
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
4B5 -
Myeloma
x63-Ag8.653 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab22626 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | (1) |
Use at an assay dependent dilution. Predicted molecular weight: 35 kDa.
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| IP |
Use at an assay dependent dilution.
|
| Notes |
|---|
|
WB
Use at an assay dependent dilution. Predicted molecular weight: 35 kDa. |
|
IP
Use at an assay dependent dilution. |
Target
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Relevance
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling. -
Cellular localization
Cell Membrane -
Alternative names
- F-protein antibody
- HIV2 nef protein antibody
- Human immunodeficiency virus 2 nef antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab22626 has not yet been referenced specifically in any publications.