- Datasheet
- Specific References
- Protocols
Overview
-
Product nameAnti-HIV2 Nef antibody [4B5]
-
DescriptionRat monoclonal [4B5] to HIV2 Nef
-
Host speciesRat
-
Tested applicationsSuitable for: WB, IPmore details
-
Species reactivityReacts with HIV2. It does not react with HIV1. Not yet tested in other species.
-
Immunogen
Fusion protein: TrpE-Fusion protein
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
-
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS -
Concentration information loading... -
PurityProtein G purified
-
ClonalityMonoclonal
-
Clone number4B5
-
Myelomax63-Ag8.653
-
IsotypeIgG1
-
Research areas
Associated products
-
Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab22626 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent dilution. Predicted molecular weight: 35 kDa. | |
| IP | Use at an assay dependent dilution. |
Target
-
RelevanceNef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
-
Cellular localizationCell Membrane
-
Alternative names
- F-protein antibody
- HIV2 nef protein antibody
- Human immunodeficiency virus 2 nef antibody
see all
References
ab22626 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"