PE Anti-HLA A2 antibody [BB7.2] (ab79523)
Key features and details
- PE Mouse monoclonal [BB7.2] to HLA A2
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2b
Related conjugates and formulations
Overview
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Product name
PE Anti-HLA A2 antibody [BB7.2]
See all HLA A2 primary antibodies -
Description
PE Mouse monoclonal [BB7.2] to HLA A2 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
HLA A2 solubilised by papain
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Epitope
This antibody recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA A2 histocompatibility antigen. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading...
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Purity
Size exclusion -
Clonality
Monoclonal -
Clone number
BB7.2 -
Isotype
IgG2b -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab79523 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use 20µl for 106 cells.
ab91532 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. Use 20µl for 106 cells/ / 100µl of whole blood. |
Notes |
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Flow Cyt
Use 20µl for 106 cells. ab91532 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. Use 20µl for 106 cells/ / 100µl of whole blood. |
Target
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Relevance
Involved in the presentation of foreign antigens to the immune system. Dimer of alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein. -
Cellular localization
Membrane; Single-pass type I membrane protein. -
Database links
- Entrez Gene: 3105 Human
- Omim: 142800 Human
- SwissProt: P04439 Human
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Alternative names
- Antigen presenting molecule antibody
- HLA A antibody
- HLA A histocompatibility type antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab79523 has been referenced in 4 publications.
- Hu Y et al. ACME: pan-specific peptide-MHC class I binding prediction through attention-based deep neural networks. Bioinformatics 35:4946-4954 (2019). PubMed: 31120490
- Liu YY et al. Identification of HLA-A2-Restricted Mycobacterial Lipoprotein Z Peptides Recognized by T CellsFrom Patients With ActiveTuberculosis Infection. Front Microbiol 9:3131 (2018). PubMed: 30622521
- Bujko A et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med 215:441-458 (2018). PubMed: 29273642
- Heigele A et al. Down-modulation of CD8aß is a fundamental activity of primate lentiviral Nef proteins. J Virol 86:36-48 (2012). Flow Cyt ; Human . PubMed: 22013062