Anti-HLA B antibody [JOAN-1] - BSA and Azide free (ab212436)
Key features and details
- Mouse monoclonal [JOAN-1] to HLA B - BSA and Azide free
- Suitable for: ICC/IF, Flow Cyt
- Reacts with: Human
- Isotype: IgG3
Overview
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Product name
Anti-HLA B antibody [JOAN-1] - BSA and Azide free
See all HLA B primary antibodies -
Description
Mouse monoclonal [JOAN-1] to HLA B - BSA and Azide free -
Host species
Mouse -
Tested applications
Suitable for: ICC/IF, Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus. Normal human peripheral blood lymphocytes.
Database link: P01889 -
Positive control
- Human peripheral blood lymphocytes. Tonsil and lymph node tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Constituent: 100% PBS -
Carrier free
Yes -
Concentration information loading...
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Purity
Protein A/G purified -
Clonality
Monoclonal -
Clone number
JOAN-1 -
Isotype
IgG3 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab212436 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
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Notes |
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ICC/IF
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. |
Target
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Function
Involved in the presentation of foreign antigens to the immune system. -
Sequence similarities
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
Post-translational
modificationsPolyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3106 Human
- Omim: 142830 Human
- SwissProt: P01889 Human
- SwissProt: P03989 Human
- Unigene: 77961 Human
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Alternative names
- 1B07_HUMAN antibody
- AS antibody
- B-4901 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (3)
ab212436 has been referenced in 3 publications.
- Young NT et al. Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation. Hum Immunol 52:1-11 (1997). PubMed: 9021404
- Krensky AM & Clayberger C Immunomodulation by HLA class I-derived peptides. Transplant Proc 28:3026-8 (1996). PubMed: 8962174
- Hansen JA et al. The HLA system in clinical marrow transplantation. Hematol Oncol Clin North Am 4:507-15 (1990). PubMed: 2193011