Overview

  • Product name

    Anti-HLA B antibody [JOAN-1] - BSA and Azide free
    See all HLA B primary antibodies
  • Description

    Mouse monoclonal [JOAN-1] to HLA B - BSA and Azide free
  • Host species

    Mouse
  • Tested applications

    Suitable for: ICC/IF, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus. Normal human peripheral blood lymphocytes.
    Database link: P01889

  • Positive control

    • Human peripheral blood lymphocytes. Tonsil and lymph node tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab212436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 0.5 - 1 µg/ml.
Flow Cyt Use 0.5-1µg for 106 cells.

Target

  • Function

    Involved in the presentation of foreign antigens to the immune system.
  • Sequence similarities

    Belongs to the MHC class I family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Post-translational
    modifications

    Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1B07_HUMAN antibody
    • AS antibody
    • B-4901 antibody
    • B-7 alpha chain antibody
    • HC class I antigen SHCHA antibody
    • HLA class I histocompatibility antigen antibody
    • HLA class I histocompatibility antigen, B alpha chain antibody
    • HLA-B antibody
    • HLA-B histocompatibility type antibody
    • HLAB antibody
    • leukocyte antigen class I-B antibody
    • major histocompatibility complex, class I, B antibody
    • MHC class 1 antigen antibody
    • MHC class I antigen B*7 antibody
    • MHC class I antigen HLA-B alpha chain antibody
    • MHC class I antigen HLA-B heavy chain antibody
    • MHC Class I HLA heavy chain antibody
    • MHC class I molecule antibody
    • MHC HLA-B cell surface glycoprotein antibody
    • MHC HLA-B transmembrane glycoprotein antibody
    • SPDA1 antibody
    see all

References

This product has been referenced in:

  • Young NT  et al. Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation. Hum Immunol 52:1-11 (1997). Read more (PubMed: 9021404) »
  • Krensky AM & Clayberger C Immunomodulation by HLA class I-derived peptides. Transplant Proc 28:3026-8 (1996). Read more (PubMed: 8962174) »
See all 3 Publications for this product

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