Overview

  • Product name

    Anti-HLA B27 antibody [EP-4]
    See all HLA B27 primary antibodies
  • Description

    Mouse monoclonal [EP-4] to HLA B27
  • Host species

    Mouse
  • Tested applications

    Suitable for: ICCmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation. Lymphocytes from HLA-B27 individual.

  • Positive control

    • Blood
  • General notes


    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Purified IgM
  • Primary antibody notes

    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.
  • Clonality

    Monoclonal
  • Clone number

    EP-4
  • Isotype

    IgM
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.

For use with paraformaldehyde fixed cell suspensions or cytospins.

Target

  • Relevance

    Involved in the presentation of foreign antigens to the immune system. HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells.
  • Cellular localization

    Single-pass type 1 membrane protein
  • Database links

  • Alternative names

    • HLAB antibody
    • Leukocyte antigen class I B antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex class I B antibody
    • SPDA1 antibody
    see all

References

ab24094 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab24094.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up