PE Anti-HLA B7 antibody [BB7.1] (ab33331)
Key features and details
- PE Mouse monoclonal [BB7.1] to HLA B7
- Suitable for: Flow Cyt
- Reacts with: Human, Monkey, Cynomolgus monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
PE Anti-HLA B7 antibody [BB7.1]
See all HLA B7 primary antibodies -
Description
PE Mouse monoclonal [BB7.1] to HLA B7 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Specificity
This antibody binds to the HLA B7 antigen and does not cross react with HLA B27 or other related HLA antigens. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human, Monkey, Cynomolgus monkey -
Immunogen
Full length protein corresponding to Human HLA B7. Papain solubilized HLA-B7 antigen.
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General notes
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
This antibody was purified from tissue culture supernatant. -
Primary antibody notes
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis. -
Clonality
Monoclonal -
Clone number
BB7.1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab33331 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use at an assay dependent concentration.
(or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. (or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Relevance
HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. -
Cellular localization
Cell Membrane, single pass type I membrane protein. -
Database links
- Entrez Gene: 3106 Human
- Omim: 142830 Human
- SwissProt: P01889 Human
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Alternative names
- Abacavir hypersensitivity, susceptibility to antibody
- Drug-induced liver injury due to flucloxacillin antibody
- HLA B antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab33331 has been referenced in 1 publication.
- Viborg N et al. T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients. Oncoimmunology 8:e1663107 (2019). PubMed: 31741759