Overview

  • Product name

    Anti-HLA B7 antibody [CATA-1]
    See all HLA B7 primary antibodies
  • Description

    Mouse monoclonal [CATA-1] to HLA B7
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human HLA B7. Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2 and DRw10.
    Database link: P01889

  • Positive control

    • IHC-P: Human tonsil tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    Purified from bioreactor concentrate by Protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    CATA-1
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab236491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.5 - 1 µg/ml.

Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes.

Incubate with primary antibody for 30 minutes at RT.

                        

Target

  • Relevance

    HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described.
  • Cellular localization

    Cell Membrane, single pass type I membrane protein.
  • Database links

  • Alternative names

    • Abacavir hypersensitivity, susceptibility to antibody
    • Drug-induced liver injury due to flucloxacillin antibody
    • HLA B antibody
    • HLA class I histocompatibility antigen B 7 alpha chain antibody
    • HLA class I histocompatibility antigen, B-13 alpha chain antibody
    • HLA class I histocompatibility antigen, B-14 alpha chain antibody
    • HLA class I histocompatibility antigen, B-15 alpha chain antibody
    • HLA class I histocompatibility antigen, B-18 alpha chain antibody
    • HLA class I histocompatibility antigen, B-27 alpha chain antibody
    • HLA class I histocompatibility antigen, B-35 alpha chain antibody
    • HLA class I histocompatibility antigen, B-37 alpha chain antibody
    • HLA class I histocompatibility antigen, B-38 alpha chain antibody
    • HLA class I histocompatibility antigen, B-40 alpha chain antibody
    • HLA class I histocompatibility antigen, B-41 alpha chain antibody
    • HLA class I histocompatibility antigen, B-42 alpha chain antibody
    • HLA class I histocompatibility antigen, B-44 alpha chain antibody
    • HLA class I histocompatibility antigen, B-45 alpha chain antibody
    • HLA class I histocompatibility antigen, B-46 alpha chain antibody
    • HLA class I histocompatibility antigen, B-47 alpha chain antibody
    • HLA class I histocompatibility antigen, B-48 alpha chain antibody
    • HLA class I histocompatibility antigen, B-49 alpha chain antibody
    • HLA class I histocompatibility antigen, B-50 alpha chain antibody
    • HLA class I histocompatibility antigen, B-51 alpha chain antibody
    • HLA class I histocompatibility antigen, B-52 alpha chain antibody
    • HLA class I histocompatibility antigen, B-53 alpha chain antibody
    • HLA class I histocompatibility antigen, B-54 alpha chain antibody
    • HLA class I histocompatibility antigen, B-55 alpha chain antibody
    • HLA class I histocompatibility antigen, B-56 alpha chain antibody
    • HLA class I histocompatibility antigen, B-57 alpha chain antibody
    • HLA class I histocompatibility antigen, B-58 alpha chain antibody
    • HLA class I histocompatibility antigen, B-59 alpha chain antibody
    • HLA class I histocompatibility antigen, B-67 alpha chain antibody
    • HLA class I histocompatibility antigen, B-7 alpha chain antibody
    • HLA class I histocompatibility antigen, B-73 alpha chain antibody
    • HLA class I histocompatibility antigen, B-78 alpha chain antibody
    • HLA class I histocompatibility antigen, B-8 alpha chain antibody
    • HLA class I histocompatibility antigen, B-81 alpha chain antibody
    • HLA class I histocompatibility antigen, B-82 alpha chain antibody
    • HLAB antibody
    • Leukocyte antigen class I B antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex class I B antibody
    • MHC class I antigen B 7 antibody
    • Synovitis, chronic, susceptibility to antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human tonsil tissue stained for HLA B7 using ab236491 at 1 μg/ml in immunohistochemical analysis.

References

ab236491 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab236491.
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